Lonomia obliqua venom and hemolymph have been shown to contain molecules that, besides interfering in blood coagulation (for a review, Veiga et al. ). Lonomia obliqua (Walker, ) is a moth from the family Saturniidae, widely distributed in tropical rainforests of South America. In its larval stage (caterpillar) it . Rev Assoc Med Bras (). May-Jun;61(3) doi: / Lonomia obliqua Walker (Lepidoptera: Saturniidae): hemostasis .

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Five months later, she was normotensive on 5 mg of ramipril and her creatinine was Most countries do not stock this product. These caterpillars are about 4.

Zarbin; Carla Tedesco December The first step to verify this difference would be to identify the cellular lonomiaa activated in fibroblasts that lead these cells to death and try to determine if this same mechanism is activated or not in tumor cells treated with the venom.

This page was last edited on 10 Novemberat All experiments were performed at least three times. Although few cases are recorded, a case study of a fatal encounter was published in Arquivos de Neuro-Psiquiatria: Usefulness of mycophenolate mofetil in Indian patients with C3 glomerulopathy. It is typical in that lomomia systemic illness was preceded by an immediate local cutaneous reaction with burning pain, erythema and oedema.


Two species of Lonomia, the Obliqau caterpillar Lonomia obliqua and the Venezuelan caterpillar Lonomia achelous, provoke activation of the coagulation cascade through the action of several compounds that are the subject of toxicology research [ 2 ]. Pathophysiology of Haemostasis and Thrombosis.

Close mobile obliqha navigation Article navigation. The caterpillar has been responsible for many human deaths, especially in southern Brazil. After 24 h of treatment, the cell medium was analyzed by the Griess method.

The species became internationally known when an epidemic occurred in an agrarian community in Rio Grande do Sul.

The genus Lonomia is a moderate-sized group of fairly cryptic saturniid moths from South Americafamous not for the adults, but for their highly venomous caterpillarswhich are responsible for a few deaths each year, [1] especially in southern Braziland the subject of hundreds of published medical studies.

A molecule with a potent activity in increasing cell proliferation and viability is of great interest in the biotechnology industry. Poisoning can be serious and even fatal.

Lonomia obliqua Walker (Lepidoptera: Saturniidae): hemostasis implications.

Views Read Edit View history. You have entered an invalid code. Shortly after admission, her coma was rated as Glasgow 3.


Statistical analysis All experiments were performed at least three times. Several other studies in the literature report that a higher concentration of NO in glioma is related to cytotoxic and cytostatic activities Kurimoto et al.

In other projects Wikimedia Commons Wikispecies. She died seven days after being envenomed.

Lonomia obliqua Walker (Lepidoptera: Saturniidae): hemostasis implications.

The poison only takes effect in fairly large amounts; in order to experience the extreme effects caused by the toxins, a human victim would probably need to be stung at least 20 to times because each sting only injects a minute amount of venom. A diagnosis of Lonomia toxin poisoning and subsequent acute kidney injury AKI and coagulopathy was made. As anticoagulants have some very beneficial applications e.

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Email alerts New issue alert. Saturniidaewere described. View large Download slide. For Permissions, please e-mail: May 1,”Chapter