Insulin lispro protamine is used to reduce high blood sugar levels in patients Insulin lispro protamine is injected under the skin. Humalog Mix KwikPen. HUMALOG é indicado no tratamento de pacientes com diabetes mellitus que necessitam .. médico e leve a embalagem ou bula do medicamento, se possível. 18 abr. B. Humalog Mix 50 Lilly (50% lispro/protamina e 50% lispro). 2,0. .. dicado em bula, o uso combinado de exanatide com.
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However, glucose solution must be given intravenously if glucagon is not available or if the patient fails to respond to glucagon. Needles are not included.
Fertility Insulin lispro did not induce fertility impairment in animal studies see section 5. Instructions for use and handling To prevent the possible transmission of disease, each pen must be used by one patient only, even if the needle is changed. The use of dosages which are inadequate or discontinuation of treatment, especially in insulin-dependent diabetics, may lead to hyperglycaemia and diabetic ketoacidosis; conditions which are potentially lethal.
Active ingredient insulin lispro. Posology The dosage should be determined by the physician, according to the requirement of the patient. Patients with diabetes who are breast-feeding may require adjustments in insulin dose, diet or both. The patient should be given a meal as soon as consciousness is recovered. Hepatic impairment Insulin requirements may be reduced in patients with hepatic impairment due to reduced capacity for gluconeogenesis and reduced insulin breakdown; however, in patients with chronic hepatic impairment, an increase in insulin resistance may lead to increased insulin requirements.
The time course of action of any insulin may vary considerably in different individuals or at different times in the same individual.
Marketing authorisation number s 9. When considering the clinical relevance of these kinetics, it is more appropriate to examine the glucose utilisation curves as discussed in 5. The markings on the insulin syringe will not measure the dose correctly. Insulin lispro did not induce fertility impairment, embryotoxicity or teratogenicity in animal studies. Use of injection sites should be rotated so that the same site is not used more than approximately once a month.
Qualitative and quantitative composition 3. A consequence of the pharmacodynamics of rapid-acting insulin analogues is that if hypoglycaemia occurs, it may occur earlier after an injection when compared with soluble human insulin. Insulin requirements usually fall during the first trimester and increase during the second and third trimesters.
Back to top Eli Lilly and Company Limited contact details. Adjustment of dosage may also be necessary if patients undertake increased physical activity or change their usual diet.
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Reporting suspected adverse reactions after authorisation of the medicinal product is important. Prescription Drug Search Strengths available for Humalog cartridge: When necessary Humalog can be given soon after meals.
Yellow Card Scheme, website: Glucodynamic differences between insulin lispro and soluble human humalgo, as measured during a glucose clamp procedure, were maintained over a wide range of renal function. It may cause a rash over the whole body, shortness of breath, wheezing, reduction in blood pressure, fast pulse, or sweating. Correction of moderately severe hypoglycaemia can be accomplished byla intramuscular or subcutaneous administration of glucagon, followed by oral carbohydrate when the patient recovers sufficiently.
Humalog 200 Units/ml KwikPen, solution for injection in pre-filled pen
Insulin requirements may be reduced in patients with hepatic impairment due to reduced capacity for gluconeogenesis and reduced insulin breakdown; however, in patients with chronic hepatic impairment, an increase in insulin resistance may lead to increased insulin requirements. Subcutaneous administration should be in the upper arms, thighs, buttocks, or abdomen. Insulin lispro maintains more rapid absorption when compared to soluble human insulin in patients with renal impairment.
Special populations Renal impairment Insulin requirements may be reduced in the presence of renal impairment. After injection, the site of injection should not be massaged.
The pre-filled pen should not be stored with the needle attached.
Humalog Reusable Discount Card: Type I glass cartridges, sealed with halobutyl disc seals and plunger heads and secured with aluminium seals. It was first approved for use in the United States inmaking it In some instances, this condition humallog be related to factors other than insulin, such as irritants in the skin cleansing agent or poor injection technique.
The advisability of driving should be considered in these circumstances. Insulins have no specific overdose definitions because serum glucose concentrations are a result of complex interactions between insulin levels, glucose availability and other metabolic processes. Eli Lilly Nederland B. Systemic allergy, which is rare but potentially bulaa serious, is a generalised allergy to insulin.
In in vitro tests, including binding to insulin receptor sites and effects on growing cells, insulin lispro behaved in a manner that closely resembled human insulin. Healthcare professionals are asked to report any suspected adverse reactions via Ireland: In some studies, reduction of nocturnal hypoglycaemia was associated with increased episodes of daytime hypoglycaemia. Drugs used in diabetes, insulins and analogues for injection, fast-acting, ATC code: Humalog insulin lispro is used to treat type 1 insulin-dependent diabetes in adults.
Hypoglycaemia and hyperglycaemia Conditions which may make the early warning symptoms of hypoglycaemia different or less pronounced include long duration of diabetes, intensified insulin therapy, diabetic nerve disease or medicinal products such as beta-blockers. Overdose can result causing severe hypoglycemia.
Insulin lispro, sold under the brand name Humalog among others, is a fast acting insulin analog.