PDF | Holarrhena antidysenterica Wall. is an important plant employed in various indigenous systems of medicine against several diseases, and almost every. Holarrhena Antidysenterica is a very significant herbal drug in Unani system of medicine and Ayurvedic system of medicine. This meticulous. Holarrhena antidysenterica. PlantID, Botanical Name, Holarrhena antidysenterica. Common Name, Kurchi. Classification.

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The symptoms were sensation of heat in abdomen and head, nausea, flatulence, constipation, agitation, nervousness and insomnia, vertigo, syncope, weakness and emptiness, xerostomia, and lightness of body. The bitter value of HA seeds is [ Figure 1 ]. It is a medicinal plant in Ayurveda. The bark is used externally in case of skin troubles. Apocynaceae Oleander family Synonyms: It is exported in the form seed powder, bark powder, kutaja kwatha, Kutaja Prapati Vati and as herbal dietary supplement.

Natidysenterica study of Holarrhena antidysenterica Wall. HA seed ethanolic extract prevents streptozotocin-induced BW loss and hyperglycemia holarehena administered for 28 consecutive days. PawarShrirang B. Short stem has pale bark and several branches. Oppositely arranges, ovate, obtusely acuminate leaves are cm long. Anti-diabetic antidgsenterica of ethanolic extract of Holarrhena antidysenterica Linn Leaves.

Application of this herb is useful in Rh. Antidiabetic, Holarrhena antidyscentricapharmacology. National Center for Biotechnology InformationU.

In vitro antioxidant activity of Holarrhena antidysenterica Wall. The antidiarrheal activity of HA root bark decoction was studied on three strains of Escherichia colii. Financial support and sponsorship Nil. Ayurvedic Pharmacopoeia of India, Part 1. Conflicts of interest There are no conflicts of interest.


Chromatographic fractionation was carried out and five steroidal alkaloids hloarrhena identified, namely, conessine, iso-conessine, connesimin, corarchimin, and conimin. Leaves 5g along with those of Picrorhiza kurroa Royale holagrhena.

J Econ Taxon Bot. Studies on the medicinal uses of plants by the Boro tribals of Assam Using activity-directed fractionation, it was revealed that the spasmogenic component was present in the aqueous fraction, while the spasmolytic component was found in the organic fraction. Seeds of HA are mainly used as an anti-diabetic remedy. The fresh juice of bark is considered good to check the diarrhoea. Abstract Holarrhena antidysenterica L.

The plant HA has the potential to develop drug against various enteric, skin diseases and diabetes. Comparative pharmacognostical, physicochemical and antibacterial studies on seeds of Holarrhena Antidysenterica wall and Wrightia Tinctoria R. Further fractions of the extract were studied, and it was observed that, chloroform-soluble fraction showed the highest anticancer potential against human cancer cell lines. Inhibitory effect of hydro-methanolic extract of seed of Holarrhena antidysenterica on alpha-glucosidase activity and postprandial blood glucose level in normoglycemic rat.

J Homeopathy Ayurvedic Med. Recent Res Sci Technol. Int J Pharm Res. The bark is mostly mixed with cow urine and apply it in affected parts.

Indrajao is a deciduous shrub or a small tree, growing up to 3 ms high. Support Center Support Center. HA has got traditional and folklore values in India. In Ayurveda, this plant is used in classical formulations, namely, Kutajarishta, Kutajavleha and Kutajghan vati, Mahamanjishtadi Kashayam, Stanyashodhana Kashaya, and Patoladi Choornam.

Plant Description

Int J Trop Insect Sci. Credibility of traditional knowledge — The criterion of multilocational and multiethnic use. The in vitro antioxidant activity of HA leaves methanolic extract using hydroxyl radical, superoxide anion scavenging, and reducing power assays was studied, and it was found to contain high radical scavenging activity and phenolic contents. According to Ayurveda, the bark is useful in treatment of piles, skin diseases and biliousness.


Indian J Tradit Knowl. The plant Holarrhena antidysenterica HAwhich is commonly known as Kutaj, and its seeds, which are known as Indrajava, are found in tropical and subtropical regions of Asia and Africa.

Hydro-alcoholic extract also showed similar results except on ovarian cancer cell line. The extracts significantly reduced parasitemia in Plasmodium berghei -infected mice as compared to chloroquine with ED 50 value at This article has been cited by other articles in PMC.

Seeds are 8 mm long or more, linear oblong, tipped with antidysrnterica deciduous coma of brown hair, 2—2. HA inhibits the stable toxin production and prevents its intestinal secretions, which leads to a decrease in the virulence of enterotoxigenic ETEC strains.

Int J Pharma Res Rev.

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Baruah P, Sarma GC. Photographs depicting the difference in stem, leaves, and pods of Holarrhena antidyscentrica left and Wrightia tinctoria right. Antibacterial activity of Kutaj Holarrhena antidysenterica Linn. It is abundant in India, especially in the Himalayan ranges.