George Nicholas Papanicolaou was born in Kimi on the island of Euboea. It is near the southern town of Karystos known for the ancient physician Diokles of. Even at a young age, George Papanicolaou envisioned himself striving to live his life out on some large, important, but as yet undefined stage. After receiving his. Georgios Nikolaou Papanikolaou was a Greek pioneer in cytopathology and early cancer George Papanikolaou In he moved to Miami, Florida, to develop the Papanicolaou Cancer Research Institute at the University of Miami, but.

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The simple procedure, now famously known as the Pap smear or test, quickly became the gold standard in screening for cervical cancer.

George Nicholas Papanicolaou |

He was thrilled when he was able to discern differences between the cytology of normal and malignant cervical cells upon a simple viewing of swabs smeared on microscopic slides. Other diagnostic tests based upon Papanicolaou’s methodology exfoliated cytology, the scraping, staining, and examination of cells from the test site proved effective in screening for abnormalities in cells from other organs and systems.

He subsequently took other jobs: For the next year he took care of patients at a leper colony north of his hometown of Kimi. Mary was both thrilled and relieved, as she was increasingly concerned over his recent distracted behaviour and fascination with dream analysis and parapsychology.

As it cost little, was easy to perform and could be interpreted nicgolas, the Pap smear found widespread use and resulted in a significant decline in the incidence of cervical cancer.

Pap-test and Babes method are not one and the same. However, his desire to work in science soon took hold and he travelled to the University of Munich in Germany, receiving a PhD georgf zoology in The diagnostic value of vaginal smears in carcinoma of the uterus.

[George Nicholas Papanicolaou].

Papanicolaou obtained American citizenship in At a medical conference in Battle Creek, Michigan, Papanicolaou introduced his low-cost, easily performed screening test for early detection of cancerous and precancerous cells.

Please login to access the full content. Fromhe began to focus on nciholas cytopathology of the human reproductive system. That papanlcolaou he had undertaken a study of vaginal fluid in women, in hopes of observing cellular changes over the course of a menstrual cycle. Papanicolaou’s test known as a Pap smear became the most effective cancer prevention method ever devised.


If so, one should be able to obtain the necessary information from the vaginal secretions. Papanicolaou and Traut argued that cancerous cervical lesions could be detected by papanicolau and measurable cellular changes while the cells were still in a preinvasive phase.

At a medical conference in Battle Creek, Michigan, Papanicolaou introduced his a low-cost, easily performed nicholzs test for early detection of the cancerous and precancerous cells. As a boy he loved outdoor life, particularly mountain hiking av boating. The diagnostic value of vaginal smears in carcinoma of the uterus After graduation, Papanicolaou worked in the military as an assistant surgeon for a short time, then returned to his hometown, Kimi.

Under the terms of the licence agreement, an individual user may print out a single article for personal use for details see Privacy Policy and Legal Notice. At Cornell for 45 years, he developed a method for studying exfoliated epithelial cells and did work which established the field of modern diagnostic cytology.

Georgios Papanikolaou – Wikipedia

Papanicolaou Society of Cytopathology. His research was devoted almost exclusively to the physiology of reproduction and exfoliative cytology, at the New York Hospital and the Cornell Medical College, two affiliated institutions, each of which has named a laboratory in his honour. This page was last edited on 22 Decemberat In he moved to Miami, Floridato develop the Papanicolaou Cancer Research Institute [3] [4] [5] at the University of Miamibut died there on 19 February [6] [7] prior to its opening.

Shortly thereafter, Papanicolaou married Andromache Mavroyeni Marywho was from a famous military family. In November Papanicolaou moved to Florida and became director of the Miami Cancer Institute, but died three months later of acute myocardial infarction.

By using this site, you agree to the Terms of Use and Privacy Policy. InPapanicolaou told an incredulous audience of physicians about the technique of gathering cellular debris from the lining of the vaginal tract and smearing it on a glass slide for microscopic examination as a way to identify cervical cancer. After serving in the army, he joined his father’s medical practice for awhile before pursuing a career in academic medicine. In —with a new wife and no firm prospects—Papanicolaou set sail for America.


Cornell University New York Hospital. An indefatigable worker, Papanicolaou is said never to have taken a vacation.

List people by country List people alphabetically List eponyms alphabetically List all women alphabetically. Author information Copyright and License information Disclaimer. He was 78 years old. American Journal of Obstetrics and Gynecology, St.

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New York,p In an attempt to test his theories in humans, Papanicolaou undertook a study of human vaginal smears. Subscribe Access to the full content requires a subscription.

However, medical history has sided with Papanicolaou as the originator of the Pap test, as the two methods were viewed to be substantially different. You do not currently have access to this article Login Please login to access the full content.

His capable wife Mary managed both laboratory and household affairs, even functioning as an experimental subject in some of his studies. In his work was honored by the U. Papanicolaou’s studies in clinical cytology were reinforced by new ways of examining disease in general, and by specific medical breakthroughs.

The study georgee science and medicine in Greece goes back as far as the history of medicine and was the home, in the late s, of Nikolas and Maria Papanicolaou a physician on the island of Euboea, Greece. Journal List Singapore Med J v. During the Balkan War,he served as second lieutenant in the medical corps of the Nciholas army, fighting the Turks. Music Politics Religion and belief Science and technology Social welfare and reform.

George Nicholas Papanicolaou

During these studies Papanicolaou noted cyclical changes in geprge vaginal discharges from test animals that Papanicolaou linked to the ovarian and uterine cycles. The test was an important milestone in medicine because it reliably discerned the earliest and most curable stage of cancer. George Nicholas Papanicolaou was born on May 13,the third child of the couple who raised him and his two sisters in the small town of Kymi where he served as physician.

In he emigrated to the U.