dalam mengidentifikasi ligan pada enzim siklooksigenase Hasil penelitian ini menunjukkan bahwa analisis. Hubungan Kuantitatif. Enzim siklooksigenase (COX) yang terlibat dalam reaksi memiliki 2 isoform, yaitu COX-1 dan COX-2 (Łanocha-Arendarczyk et al., ; Stolfi et al., ). Studi In Silico Senyawa Alkaloid Herba Bakung Putih (Crinum Asiaticum L.) pada Penghambatan Enzim Siklooksigenase (COX).

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Penapisan Virtual Senyawa Turunan Metil Sinamat Pada Enzim Siklooksigenase-2 (Cox-2 – Neliti

Penghambatan Enzim Siklooksigenase-2 oleh campuran nanopartikel ekstrak Suruhan Peperomia pellucida dan Jahe Merah Zingiber officinale. Collections UT – Biochemistry [].

Keywords Cyclooxygenase, Crinum asiaticum L. Abstract Inflammation is a response to tissue injury involving the physiological process of cyclooxygenase enzyme activation which has two isoforms, cyclooxygenase-1 COX-1 and cyclooxygenase-2 COX-2 enzymes.

The results of drug scans, hippadin, pratorimin and lycobetaine have the criteria for oral preparations. Inflammation is a response to tissue injury involving the physiological process of cyclooxygenase enzyme activation which has two isoforms, cyclooxygenase-1 COX-1 and cyclooxygenase-2 COX-2 enzymes.

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Abstract Both suruhan Peperomia pellucida and red ginger Zingiber officinale were known to inhibit cyclooxygenase-2 but, the mixture of these two has a low inhibition of cyclooxygenase The objective of this study was to find out eight active white herbic alkaloid compounds Crinum asiaticum L. Author Astiati, Ukdiah Tiara. The aim of this research is to test the potency of suruhan, red ginger, and its mixture in nanoparticle as a cyclooxygenase-2 inhibitor.

Molecular docking method for the prediction of complex structures of proteins called ligand-protein docking using the PLANTS 1.

Nanoparticle of suruhan did not have an inhibitory effect, however its mixture with nanoparticle of red ginger 1: Average size of red ginger nanoparticle was Maximum inhibition of cyclooxygenase-2 siklooksigenqse nanoparticle of red ginger was The average size of suruhan nanopaticle was Some features of this site may not work without it.

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Metadata Show full item record. Molecular docking in COX-2 shows lycobetaine These results show that the white lycopene alkaloid compounds hyppadine, pratorimin and lycobetaine have better affinity and stability than the comparative compounds.

Groups were divided into suruhan nanoparticle, red ginger nanoparticle, and suruhan-red ginger nanoparticle 1: Nanoparticle was made using homogenation and ultrasonication.