CLSI HA5 Collection, Transport, and Processing of Blood Specimens for Testing Plasma-Based Coagulation Assays and Molecular Hemostasis Assays;. CLSI HA5. Collection, Transport, and Processing of Blood Specimens for Testing Plasma-Based Coagulation Assays; Approved Guideline. HA5 does not provide general guidelines for the performance of coagulation testing. Performance guidelines for specific coagulation assays are addressed.

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Where semi-quantitative estimates are in use, their equivalence to a conventional unit e. Standards Subsctiption may be the perfect solution. Support Center Support Center. You may delete a document from your Alert Profile at any time. If the document is revised or amended, you will be notified by email. Journal List Clin Biochem Rev v.

The interference with immunoassays is less frequent than with photometric assays, but is still a significant consideration; one of the most commonly affected immunoassays are the cardiac Troponin assays. Actions in Response to Haemolysis S4.

Example of a Haemolysis Colour Chart which also shows haemolysis index concentration levels across different analytical platforms Courtesy Goce Dimeski, Pathology Queensland. The contents of articles or advertisements in The Clinical Biochemist — Reviews are not to be construed as official statements, evaluations or endorsements by the AACB, its official bodies or its agents.


Areas to consider could include data mining, guidance on how to perform in-house studies and the defining of appropriate action limits. Best Practices in Phlebotomy. You can download and open this file to your own computer but DRM prevents opening this file on another computer, including a networked server.

The interference can be the result of various mechanisms including:. Please first log in with a verified email before subscribing to alerts. Whole Blood Analyses S5. As the voice of c,si U. Quantitative Estimation of Haemolysis S2.

Laboratories must monitor the frequency of haemolysed blood cls and investigate the source of collection to enable continuous improvement. Laboratories must be familiar with best practice collection processes.

Clin Chem Lab Med. This decision should be guided by a policy developed in consultation with requesting clinicians. Haemolysis as influence and interference factor.

Factors Affecting Haemolysis, specimencare.

Consensus Statement for the Management and Reporting of Haemolysed Specimens

The most frequently encountered causes of haemolysis of blood samples include use of inappropriately small gauge needles during phlebotomy and transfer of blood from a syringe into a vacutainer tube via a needle e. Additive – as result of greater concentrations of analytes in cells than in plasma e. Statements of opinion in AACB publications are those of the contributors. Best Practice Collection Technique S1.


Proceed to Checkout Continue Shopping. ISSN — The H-index at which a clinically relevant effect is seen must be determined for each method in use. The interference can be the result of various mechanisms including: Enzymatic – release of enzymes which degrade analytes e. Similarly, brown coloured serum due to methaemalbumin, normal results for potassium or the same result from arterial and venous collections should prompt further investigation e.

Cut-offs at which assays are affected must be reviewed and updated when analytical platforms are changed. This standard is also available to be included in Standards Subscriptions. Please first verify your email before subscribing to alerts. Observational study to determine factors associated with blood sample haemolysis in the emergency department.

Best Practices in Phlebotomy Ann Acad Med Singapore.

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Consensus Statement for the Management and Reporting of Haemolysed Specimens

Already Subscribed to this document. Find articles by Ken Sikaris. Laboratories must have a means to identify affected patient results e.