Download Citation on ResearchGate | Cancer de la ampolla de Vater | The authors report the results of studies on five patients -3 males and 2 females- with . Periampullary tumors are neoplasms that arise in the vicinity of the ampulla of Vater. Neoplasms that arise in this site can originate from the. Metastasis of breast cancer to major duodenal papilla Palabras clave: Ampolla de Vater; Neoplasias de la mama; Ictericia (fuente: DeCS BIREME).

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One possible cause of impaired drainage of pancreatic juice is blockage of the sphincter of Oddi. Carcinoma of the ampulla of vater. Since EGFR overexpression strongly correlates with tumor progression in biliary cancer[ 72 ], the use of anti EGFR seems to be a promising therapeutic option. The second and third portions of the duodenum are mobilized en bloc with the periduodenal nodal tissue.


However, well conducted prospective clinical trials are needed to understand the role of such drugs in ampullary cancer. To date, there are no consistent data concerning biliary tree tumors and antiangiogenic drugs and only a few studies concerning anti-epidermal growth factor receptor EGFR drugs. Carcinoma of the pancreatic head dde periampullary region. In this report we present a case of biliary obstruction due to metastatic breast cancer to the major duodenal papilla.


Tumors of ampulla of Vater: A case series and review of chemotherapy options

Toh et al reported 25 patients 13 men, 12 women with a median age of 65 years who had an ampullary tumor. Demographics, histological features, stage, treatment received and outcome of 20 cases of ampullary carcinoma.

Based on their epithelium of origin, two subtypes of ampullary carcinoma have been recently distinguished: This study evaluates histopathological features and outcomes of ampullary carcinoma and to compares the survival of these tumors to that of other biliary tract tumors. National Center for Biotechnology InformationU.

Ampolla de Vater; Neoplasias de la mama; Ictericia fuente: Long-term survival and metastatic pattern of pancreatic and periampullary cancer after adjuvant chemoradiation or observation: Tumor of the ampulla of Vater: Biology portal Medicine vqter. Table 3 Studies on adjuvant chemo-radiotherapy.

Overall, a RR of Fater to the Kimura classification[ cabcer ], ampullary cancers were divided in intestinal and pancreatobiliary, depending on their histological differentiation.

Histopathology, molecular dancer and clinical outcome clearly identify two distinct types of ampullary cancer, and their differences should be taken into account both in selecting medical treatments and in planning clinical trials. Published online Mar Share Email Print Feedback Close.

Adjuvant radiotherapy and 5-fluorouracil after curative resection of cancer of the pancreas and periampullary region: Treatment options for advanced or unresectable stages vter discussed below.



Long-term survival and recurrence patterns in ampullary cancer. Yamaguchi K, Enjoji M. A multicenter, randomized phase II trial of gemcitabine and oxaliplatin GEMOX alone or in combination with biweekly cetuximab in the first-line treatment of advanced biliary cancer: Peripancreatic lymph nodes are included with the resection.

GI continuity is restored with a duodenojejunostomy. Predictors for patterns of failure after pancreaticoduodenectomy in ampullary cancer. In clinical trials concerning chemotherapy treatments, tumors of the ampulla of Vater are usually included in the group of pancreato-biliary tumors, although some data recognize their histological and clinical peculiarities.

Adjuvant intra-arterial chemotherapy and radiotherapy versus surgery alone in resectable pancreatic and periampullary cancer: Following ampullary carcinoma resection, survival appears to be intermediate between duodenal and pancreatic or distal bile duct cancer[ 21314 ].

Ampullary carcinoma, Chemotherapy, Radiotherapy, Biliary tract cancer. Chemotherapy improves survival and quality of life in ampollz pancreatic and biliary cancer. Fluoropyrimidines, cisplatin, and gemcitabine are the most commonly used drugs in ampullary carcinoma, but the best combination and protocol remain to be identified.

Prognostic impact of perineural invasion following pancreatoduodenectomy with lymphadenectomy for ampullary carcinoma.