Fairbrother KJ, Heasman PA: Anticalculus agents. J Clin Periodontol ; the research associated with the development of anticalculus agents and to evalu-. Request PDF on ResearchGate | Anticalculus agents | Most dentifrices and some mouthrinses now contain 1 or more active anticalculus agents to achieve. With the help of antiplaque and anticalculus agents. Chemical plaque control – Rationale. Gingivitis & periodontitis are highly prevalent diseases and.

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Dentifrice with improved cleansing and polishing action – contg. All percentages given are by weight of the composition unless otherwise indicated. A dentifrice may include further optional ingredients such as adhesives, sudsing agents and abrasives.

Tetrasodium pyrophosphate and sodium tripolyphosphate are anticalculus agents.

The oral care composition of claim 1, wherein the anticalculus agent comprises a zinc ion source. The composition of any of Claims wherein the pH of the anticalcu,us is above pH 7; preferably above 7. This invention also involves agentx for treating or preventing dental plaque, calculus, gingivitis, or malodor of the oral cavity comprising amdinistering to the oral cavity of a human or other animal a safe and effective amount of such compositions.

EBSCOhost | | An Overview on anticalculus agents – A review.

Suitable bleaching agents include organic and inorganic oxidizing agents such as hydrogen peroxide, alkali metal peroxides and superoxide and organic peroxides such as monoper- oxyphthalates and perbenzoic derivatives. The compositions may be applied to the subject in any suitable manner known in the art such as, for example, by introducing the composition to the subjects oral cavity using a suitable applicator or delivery device such as a brush, dental strip, film, syringe, tape, pill or any other applicator or delivery device known in the art.

Request for preliminary examination filed prior to expiration of 19th month from priority date pct application filed before After one week, the person has significantly less plaque on his teeth than he did after the first week. The oral care composition of claim 1, wherein the anticalculus agent consists essentially of a zinc ion source.


Anti-plaque and Anti-calculus Oral Care Product Testing

Such components include, but are not limited to, anticaries agents, antiplaque agents, anticalculus agents, dental abrasives, surfactants, flavoring agents, sweetening agents, binders, humectants, thickening agents, buffering agents, preservatives, coloring agents and pigments, ethanol and water.

Through our network of over 43, people in 1, laboratories and offices in countries, Intertek provides quality and safety solutions to a anticslculus range of industries around the world.

Likewise, the amount of pyro relative to to the amount of zinc is at least 1 when zinc is 1 i. Applicants have surprisingly found that certain ratios of zinc: Calculus may be white or yellowish in color or may be stained or discolored by extraneous agents. Another optional component of the oral carriers of the compositions of this invention is a humectant. Other preferred compositions of this invention are mouthwashes, mouth sprays, and dental solutions.

Suitable humectants for use in compositions of this invention include edible polyhydric alcohols such as glycerin, sorbitol, xylitol, polyethylene glycol, and propylene glycol, especially sorbitol and glycerin. The pH of oral compositions of this invention is critical but can be varied to some extent. Formally confirming that your products and services meet all trusted external and internal standards. The amounts of pyro and citrate are expressed in terms of a ratio to the amount of zinc in the oral composition.

While there is no complete agreement on the route by which precipitated calcium and orthophosphate ultimately become the crystalline material called hydroxyapatite HAPit is generally agreed that at higher saturations above the critical saturation limit the precursor to crystalline HAP is an amorphous or microcrystalline calcium phosphate.


After one week he receives dental prophylaxis performed by his dentist. As plaque and calculus continue to build up, the gums begin to recede from the teeth and pockets form therebetween, which ultimately may result in destruction of the bone and periodontal ligament.

Preferred precipitated silica materials include those marketed by the J. In certain embodiments, extracts of Magnolia Cortex the bark of Magnolia officinalis contain active compounds including: For this reason they are preferred for use herein.

Suitable sources of pyro ions are disclosed in U. The disks may be obtained from Clarkson Chromatography Products Inc. Magnolol and honokiol are non-ionic hydroxybiphenyl compounds, the gaents of which are represented as follows:.

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At the end of the test the residual biofilm is dissolved in acid and tested for calcium content using inductively coupled plasma – optical emission spectroscopy ICP-OES which is conducted in a Good Clinical Practice GCP compliant laboratory. In common with other carrier components, in certain embodiments, the surfactant should be phosphate-free.

Such topical oral carrier, when combined with Actives of this invention, results in a composition which is administered topically to the antlcalculus cavity. Enabling you to identify and mitigate agengs intrinsic risk in agentw operations, supply chains and business processes.

Saliva supernatant is obtained by centrifuging whole saliva for 10 minutes at 10, RPM. Binders and thickening agents are generally present in the compositions of this invention in combined amounts of from about 0. Auditing Consulting Sourcing Training.